I heard the following from Mrs. Dina Schoonmaker.
How do we achieve menuchas hanefesh? We learn it from menuchas Shabbos. No matter what’s going on, we stop doing our work when Shabbos comes and it’s “as if it has already been done” (Rashi). Well, what if it’s not?
Say you’re in Israel and you have a business partner in America. You’re working on something and Shabbos is coming but you feel calm because you know that your partner in another time zone is taking care of it.
That’s how we have menuchas hanefesh. Hashem lives outside of time. We don’t have to worry about how things will end because we know that Hashem has already taken care of the end. And Hashem Who loves us is happy with that end.